Phosphine-mediated cyclization leads to cyclopropa[c]coumarin structures, suggesting a new synthetic route.
A phosphine-mediated [2+1] annulation of coumarins with α-keto esters or isatins was reported, leveraging in situ-generated K-R adducts as key intermediates to efficiently access both cyclopropa[c]coumarin cores and spirooxindole-fused cyclopropa[c]coumarin...
No takes yet. Share an insight, caveat, or question.
Xiang et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: