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This research aims to evaluate the effects of sodium-glucose cotransporter 2 inhibitors on kidney diseases unrelated to diabetes.

April 22, 2026

Sodium-Glucose Cotransporter 2 Inhibitors in Kidney Diseases Other Than That Due to Diabetes: Benefits in Composite Renal Outcomes Driven by Immunoglobulin A Nephropathy.

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This research aims to evaluate the effects of sodium-glucose cotransporter 2 inhibitors on kidney diseases unrelated to diabetes.
Assessment of SGLT2 inhibitors in a population with chronic kidney disease.
Comparison of renal outcomes in patients with and without diabetes.
Focus on benefits attributed specifically to immunoglobulin A nephropathy.
SGLT2 inhibitors show positive effects on composite renal outcomes.
Benefits appear to be significantly influenced by immunoglobulin A nephropathy.
Improvements in kidney function noted across various patient groups, regardless of diabetes status.

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Research shows that SGLT2 inhibitors improve kidney health in conditions like IgAN, highlighting therapeutic potential.

Roy et al. (2026) studied this question.

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