Thiosulfonate synthesis via halothiolation of aryne intermediates followed by oxidative S -sulfonylation

Key Points

• The research aims to develop an efficient method for the synthesis of aryl thiosulfonates using aryne intermediates.
• Used aryne halothiolation with potassium xanthate to create aryl xanthates.
• Transformed aryl xanthates into thiosulfonates utilizing iodine and sodium hydroxide.
• Successfully synthesized aryl thiosulfonates with high efficiency.
• Demonstrated the effective transformation of aryne intermediates into desirable products.