Enhancing dissolution of poorly water-soluble prednisolone via spray-dried arabinoxylan microspheres: a novel arabinoxylan-based drug delivery system | Synapse
April 22, 2026Drug Development and Industrial Pharmacy0 citations
The central aim is to enhance the dissolution of poorly water-soluble prednisolone using arabinoxylan-based microspheres.
Utilized spray-drying to create arabinoxylan microspheres.
Conducted dissolution tests to evaluate the drug release profile.
Significant enhancement in the dissolution rate of prednisolone with arabinoxylan microspheres.
Arabinoxylan showed promise as a biocompatible and scalable excipient.
Abstract
Spray-dried AX microspheres significantly enhanced prednisolone dissolution, highlighting AX as a biocompatible, scalable, and promising excipient for poorly water-soluble drugs.