Case report reveals autoimmune encephalitis after gastrointestinal prodrome, suggesting diagnostic complexities.
Anti-NMDAR encephalitis is an autoimmune neurological disorder characterized by neuropsychiatric symptoms, seizures, and altered consciousness. We report a 35-year-old female who presented in March 2025 with gastrointestinal symptoms followed by encephalopathy and seizures. Investigations revealed lymphocytic cerebrospinal fluid (CSF), diffuse slowing on electroencephalography, and parieto-occipital cortical changes on MRI, with weakly positive anti-NMDAR antibodies. The patient showed significant clinical improvement following corticosteroids and plasma exchange. This case highlights the diagnostic challenge of autoimmune encephalitis presenting with gastrointestinal prodrome and elevated inflammatory markers mimicking infection.
No takes yet. Share an insight, caveat, or question.
Khalid et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: