What does this research mean for the field?

Meckel diverticulum is a congenital remnant of the omphalomesenteric duct with a global prevalence of 0.2-4%, which is managed conservatively when asymptomatic and surgically via diverticulectomy or resection when symptomatic. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To explore the characteristics and clinical significance of Meckel diverticulum (MD) and its variations.

April 23, 2026Newborn1 citationsOpen Access

Meckel Diverticulum

AKAtul Kumar KhareSawai ManSingh Medical College and Hospital

Key Points

To explore the characteristics and clinical significance of Meckel diverticulum (MD) and its variations.
Descriptive analysis of Meckel diverticulum and its variants
Review of associated congenital anomalies and diagnostic methods
Discussion of treatment options including diverticulectomy
Prevalence of Meckel diverticulum is consistently between 0.2-4% globally
Variants of Meckel diverticulum include patent omphalomesenteric duct and umbilical cysts
Symptomatic diverticula are treated surgically, while asymptomatic cases can be managed conservatively

Abstract

Meckel diverticulum (MD) is a congenital pouch on the antimesenteric border of the distal ileum.It is a remnant of the omphalomesenteric (vitelline) duct.These anomalies are seen all over the world with a fairly consistent prevalence of 0.2-4%.There is no strong evidence for genetic factors.There can be seen three possible variants: (1) an MD with the rest of the omphalomesenteric duct (OMD) seen as a terminal fibrous band connecting with the umbilicus; (2) the whole OMD remains patent; and (3) an umbilical cyst, a fluid-filled remnant in a part of the ductal pathway.The cause is unknown; no single gene mutation has been consistently associated with MDs, but new information is emerging about the pathogenesis of gut heterotopias.Some of these diverticula are seen in patients with trisomy 13, trisomy 18, trisomy 21, or with broader patterns of multiple congenital anomalies, including the Vertebral, Anal, Cardiac, tracheoesophageal, Renal, Limb anomalies (VACTERL) association.Meckel diverticulums can be associated with fibrous peritoneal bands, which can be associated with mechanical intestinal obstruction by kinking, compressing, or entrapping small bowel loops.Symptomatic cases may be diagnosed with a nuclear medicine technetium-99m pertechnetate Meckel scan that detects gastric tissue.Asymptomatic patients may be closely followed with conservative management.However, for symptomatic cases, a diverticulectomy is performed, and the fibrous bands or adhesions are released.If the base is broad, a segmental ileal resection is considered.

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