What question did this study set out to answer?

The aim is to describe a new survey for assessing readiness to change dietary habits among individuals with cognitive decline.

April 23, 2026Gut Microbiome0 citationsOpen Access

Evaluating the Gut Microbiome, Dietary Patterns, & Cognition: A Sub-study Protocol from the Brain Health & the Gut Microbiome Study in Cognitive Decline (bMicrobiome Study)

KSKarol SuchowieckiUConn Health PCPatrick CorrGeorge Washington University ASAidan SchurrGeorge Washington University

Key Points

The aim is to describe a new survey for assessing readiness to change dietary habits among individuals with cognitive decline.
Conducting a sub-study within a larger observational study
Gathering gut microbiome profiles and cognitive assessments from 45 participants
Developing and implementing a 32-item survey on readiness to change nutritional habits.
The RCNH survey was successfully developed and integrated into the study protocol.
Data collection procedures and future exploratory analyses were detailed.
This work supports the relationship between dietary habits, gut microbiome, and cognitive health.

Abstract

Objectives: To describe the development and implementation of a novel Readiness to Change Nutritional Habits (RCNH) survey for use along with dietary assessment and gut microbiome profiling in a proof-of-concept study in individuals with early Alzheimer's disease dementia (eAD), mild cognitive impairment (MCI), and healthy controls (HC).Overall, this methods paper contributes to emerging research examining how behavioral readiness for change can be integrated with dietary assessment and gut microbiome profiling to better understand the microbiome's influence on the nervous system.Methods: This is a sub-study embedded within a multi-prong proof-of-concept, observational study mapping the gut microbiome in 45 participants (15 HC, 15 MCI, 15 eAD) at baseline, 3 months, and 6 months.The parent study collects gut microbiome profiles, dietary patterns, and cognitive assessments.The sub-study develops and administers the 32 item RCNH survey to characterize participants' readiness to adopt nutritional change.Results: This manuscript reports the RCNH survey, its development process, the sub-study protocol including data collection procedures and planned exploratory analyses.Discussion: This protocol presents a novel intervention to assess the gut microbiome, individual dietary patterns, and readiness to make lifestyle change related to diet.

问 AI

Bookmark

View Full Paper