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April 23, 2026ACS OmegaOpen Access

Bridging Simulation and Sustainability: Laccase Immobilization on Bio-Polymeric Hybrids for Degradation of 17α-Ethinylestradiol in Water Systems

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Authors

ARAgnieszka RybarczykPoznań University of TechnologyPSPranchal ShrivastavaIndian Institute of Technology BhilaiRMRukmankesh MehraIndian Institute of Technology Bhilai

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Implication

This research demonstrates laccase immobilization for EE2 degradation in water systems, suggesting an effective bioremediation approach.

Key Points

  • The aim is to develop and characterize a biocatalytic system with laccase immobilized on PS-chitosan to degrade 17α-ethinylestradiol.
  • Synthesis of polystyrene-chitosan using electrospinning.
  • Immobilization of laccase from Trametes versicolor with an 87% yield.
  • Assessment through FTIR, CLSM, SEM, and kinetic analyses.
  • Laccase maintained 83% activity retention upon immobilization.
  • The system achieved 86% EE2 removal in model samples and 44% in real wastewater.
  • Molecular docking revealed enzyme binding sites with favorable interactions.

Cite This Study

Rybarczyk et al. (2026) studied this question.

synapsesocial.com/papers/69e9b62685696592c86eae04https://doi.org/10.1021/acsomega.5c13237
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