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April 23, 2026CureusOpen Access

Reverse Takotsubo Cardiomyopathy: A Case Report

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Population

A 25-year-old female who developed acute heart failure with reduced ejection fraction following a ground-level fall resulting in a subdural hematoma

Design

Case report

Key result

A 25-year-old female developed reverse Takotsubo cardiomyopathy following a traumatic subdural hematoma and fully recovered with supportive care.

Authors

AWAbigayle WyerLCLucas N CanaanSBSamuel Berding

Discussion

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Overview

Reverse TCM merits differential consideration in young patients with acute HFrEF after traumatic SDH; leaves open neurogenic triggers and requires prospective study.

Key Points

  • To present a case of reverse takotsubo cardiomyopathy and its clinical implications.
  • Case report of a 25-year-old female with acute heart failure after a ground-level fall.
  • Evaluation included clinical presentation and imaging findings consistent with reverse TCM.
  • The patient exhibited basal akinesis with preserved apical function.
  • Hospital course detailed heart failure management and recovery after diagnosis.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
1 25-year-old female who developed acute heart failure with reduced ejection fraction following a ground-level fall resulting in a subdural hematoma (SDH).
I
Intervention
Supportive care including craniotomy, intubation, vasopressors, and inotropes (milrinone)
O
Outcome
Resolution of cardiomyopathy findings on transthoracic echocardiogram

This case demonstrates that reverse Takotsubo cardiomyopathy can be triggered by traumatic subdural hematoma and can fully resolve with temporary inotropic and vasopressor support.

Cite This Study

Wyer et al. (2026) conducted a case report in Reverse Takotsubo Cardiomyopathy (n=1). Supportive care was evaluated. A 25-year-old female developed reverse Takotsubo cardiomyopathy following a traumatic subdural hematoma and fully recovered with supportive care.

synapsesocial.com/papers/69e9b62685696592c86eae82https://doi.org/10.7759/cureus.107417
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