Self-compassion as a well-being strategy against burnout among dentists: a controlled intervention study

The dental profession is inherently demanding, often leading to chronic stress and an increased risk of burnout among practitioners. Burnout has been associated with dysregulation of the hypothalamic-pituitary-adrenal axis, alterations in cortisol levels, and heightened inflammatory responses. Mindfulness-based self-compassion (MBCL) training has emerged as a promising approach for mitigating occupational stress and supporting well-being. This controlled intervention study examined the associations between an 8-week MBCL program and biochemical markers (cortisol, interleukin-6, interleukin-1β, and oxytocin), as well as psychological outcomes (burnout, mindfulness awareness, self-compassion, and anxiety) in dentists. A total of 49 participants were allocated to either the MBCL training group or a control group. Following the intervention, participants in the MBCL group showed lower IL-6 and IL-1β levels, a more adaptive diurnal cortisol pattern, and higher oxytocin levels compared with controls. In addition, reductions in burnout and anxiety scores, as well as increases in self-compassion and mindfulness awareness, were observed in the MBCL group. These findings suggest that MBCL training may be associated with improvements in psychological well-being and stress-related biochemical markers among dentists. However, given the non-randomized design and relatively small sample size, the results should be interpreted as preliminary and hypothesis-generating rather than causal. ClinicalTrials.gov NCT06804720 registration date 20/01/2025.