Background: Road traffic accidents (RTA) are a major cause of death, disability, and emergency care burden worldwide. This review synthesizes clinical predictors of severe outcomes and mortality in RTA patients presenting to emergency departments or related acute hospital settings. Methods: A systematic review was conducted using PubMed, Web of Science, Scopus, and Embase. Original studies reporting mortality, severe injury, disability, poor outcome, or related severe consequences in RTA patients were eligible. Screening followed a PRISMA-style process. Data were extracted on study characteristics, outcomes, and reported predictors. Findings were synthesized qualitatively. Results: Eight studies were included. Most were prospective, retrospective, cross-sectional, or cohort designs. Sample sizes ranged from 211 to 1,471 participants. Mortality ranged from 3.6% to 14.69%. Severe injury prevalence reached 36.4%, while permanent disability ranged from 4.6% to 6.1% in reported studies. Important predictors of poor outcome included low Glasgow Coma Scale, hypotension or systolic blood pressure ≤89 mmHg, head injury, multiple trauma, high injury severity, ICU admission, complications during treatment, delayed presentation, lack of first aid, lack of ambulance transport, comorbidity, rural residence, and pedestrian status. Conclusion: Predictors of severe outcomes and mortality in the included studies were severe neurological impairment, hemodynamic instability, advanced injury burden, and delayed access to care.
Alanazi et al. (Mon,) studied this question.