A case report highlights the risk of malignancy in young adults with peripheral nerve sheath tumors, indicating the need for careful surveillance.
This case underscores that a large, well-circumscribed retroperitoneal peripheral nerve sheath tumor in a young adult may still be malignant. Pathology-driven risk stratification with quantified mitotic activity and Ki-67 is essential for accurate classification and for planning structured post-resection surveillance.
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Senjab et al. (2026) studied this question.
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