What question did this study set out to answer?

April 23, 2026JAC-Antimicrobial ResistanceOpen Access

Clinical effectiveness and pharmacoeconomic impact of long-acting lipoglycopeptides in a multicenter outpatient day hospital model: a real-world Italian study

View Full Paper

Ask AI

Bookmark

Authors

AFA FranzòMartin University AMA MarinoOspedale Garibaldi ERE Venanzi RulloMartin University

Discussion

Member takes

Implication

Retrospective multicenter study demonstrates clinical non-inferiority and economic efficiency of LALs in adults, indicating a reform in treatment approaches.

Key Points

This research aims to assess the clinical effectiveness and pharmacoeconomic impact of long-acting lipoglycopeptides in outpatient settings.
Conducted a retrospective multicenter study across Italian specialized centers.
Analyzed clinical cure rates and pharmacoeconomic outcomes in patients treated with dalbavancin or oritavancin.
Compared the outpatient Day Hospital model to a Standard of Care inpatient approach for economic evaluations.
Achieved an overall clinical success rate of 86.9% without a significant difference in registered versus off-label infections.
Generated direct healthcare savings exceeding €629,000 by reducing inpatient bed days and preventing lost workdays.
Avoided 7.2 healthcare-associated infections, translating to additional savings in management costs.

Cite This Study

Franzò et al. (2026) studied this question.

synapsesocial.com/papers/69e9b7c585696592c86eb6bf https://doi.org/10.1093/jacamr/dlag046.002

View Full Paper

Ask AI

Bookmark

Implication

Retrospective multicenter study demonstrates clinical non-inferiority and economic efficiency of LALs in adults, indicating a reform in treatment approaches.

Clinical effectiveness and pharmacoeconomic impact of long-acting lipoglycopeptides in a multicenter outpatient day hospital model: a real-world Italian study

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical effectiveness and pharmacoeconomic impact of long-acting lipoglycopeptides in a multicenter outpatient day hospital model: a real-world Italian study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider