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April 23, 2026JCEM Case ReportsOpen Access

Drug-induced liver injury due to potassium iodide during thyroid storm

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Authors

NTNoriyoshi TakanoYSYasufumi SekiDWDaisuke Watanabe

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Overview

Case report identifies potassium iodide as a potential cause of liver injury in thyroid storm, indicating caution during treatment.

Key Points

  • To report a case of potassium iodide-induced liver injury during treatment for thyroid storm in a patient with Graves disease.
  • Case report of a 30-year-old man with thyrotoxicosis due to Graves disease and thyroid storm.
  • Treatment included methimazole, potassium iodide, corticosteroids, and beta-blockers.
  • Lymphocyte transformation tests were conducted to assess drug-induced liver injury.
  • Total bilirubin levels increased significantly to 32.4 mg/dL after potassium iodide treatment.
  • Bilirubin levels decreased rapidly after discontinuation of potassium iodide.
  • Lymphocyte transformation tests confirmed the diagnosis of potassium iodide-induced liver injury.

Cite This Study

Takano et al. (2026) studied this question.

synapsesocial.com/papers/69e9b80e85696592c86eb755https://doi.org/10.1210/jcemcr/luag053
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