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Immunohistochemical study investigates hemidesmosomal protein expression in oral cancer, suggesting enhanced digital analysis improves understanding of tissue heterogeneity.
Our findings highlight the importance of biologically targeted region-of-interest selection when assessing hemidesmosomal protein expression in OSCC while demonstrating that BMZ-focused digital analysis provides a more informative approach for exploratory evaluation of heterogeneous human tissues alongside progression-associated patterns observed in a murine model.
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Mongia et al. (2026) studied this question.
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