Findings demonstrate triazole resistance mutations in Aspergillus fumigatus isolates, suggesting further genetic exploration is needed.
Our findings demonstrate the range of mutations affecting triazole resistance among US isolates and provide a much-needed side-by-side comparison of the impact of these variants on the most currently used mould-active triazole antifungals. Moreover, they underscore the extent to which triazole resistance remains unexplained by known genetic determinants and the need for further discovery.
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Londoño et al. (2026) studied this question.
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