What question did this study set out to answer?

The research aims to evaluate the effects of GLP-1 receptor agonist therapy combined with lifestyle interventions on body composition and metabolic risk in adolescents with obesity.

April 23, 2026Acta Paediatrica0 citationsOpen Access

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Dynamics of Body Composition and Metabolic Risk in Adolescents With Obesity Under GLP ‐1 Receptor Agonist Therapy

ALAdar LopezTel Aviv Sourasky Medical Center LPLiat PerlTel Aviv University ECEyal Cohen‐SelaTel Aviv University

Key Points

The research aims to evaluate the effects of GLP-1 receptor agonist therapy combined with lifestyle interventions on body composition and metabolic risk in adolescents with obesity.
Analyzed body composition changes in adolescents with obesity
Implemented GLP-1 receptor agonist therapy alongside lifestyle interventions
Assessments focused on metabolic syndrome components
Participants showed significant improvements in body composition metrics.
Notable reductions in metabolic syndrome components were observed.
Improved health outcomes suggest effective obesity management strategies.

Abstract

Adolescents with obesity under GLP-1 RA therapy combined with lifestyle intervention demonstrated improvements in body composition and MetS components.

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Dynamics of Body Composition and Metabolic Risk in Adolescents With Obesity Under GLP ‐1 Receptor Agonist Therapy

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Abstract

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