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April 23, 2026Pain

Predictors of patient treatment adherence and moderators of response for a randomized clinical trial comparing remote cognitive behavioral therapy approaches for high-impact chronic musculoskeletal pain

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Authors

ACAndrea J. CookRWRobert WellmanMMMeghan Mayhew

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Overview

Randomized clinical trial assesses treatment adherence and intervention effectiveness in chronic pain, suggesting flexibility in care approaches.

Key Points

  • This research aims to identify factors influencing patient adherence and intervention effectiveness in remote cognitive behavioral therapy for chronic pain.
  • Conducted a large-scale 3-arm pragmatic trial comparing two remote CBT-CP approaches and usual medical care.
  • Evaluated the impact of patient session adherence and various moderators on pain severity outcomes.
  • Analyzed demographic, social, and clinical factors as potential moderators of treatment effectiveness.
  • The health coach program was more effective than the online program for men and individuals with depression.
  • Session adherence was significantly higher in the health coach program (70.4%) compared to the online program (47.8%).
  • Both interventions showed similar pain severity outcomes among completers, indicating effectiveness with proper adherence.

Cite This Study

Cook et al. (2026) studied this question.

synapsesocial.com/papers/69e9b95b85696592c86ec250https://doi.org/10.1097/j.pain.0000000000003971
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