A decade of change: evolving epidemiology of invasive pulmonary mold infections in hematologic malignancy patients from a longitudinal infection control surveillance program

Epidemiologic trends in pulmonary mold infections were assessed. Of 227 infections, 24 were considered late-onset (>14 days) and Aspergillus less common (58.3% vs 78.3%; P = .030). For late-onset cases, Aspergillus was dramatically less frequent from 2020-2025 compared to 2014-2019 (11.1% vs 86.7%, P < .001), while Fusarium spp. increased (44.4% vs 0%, P = .012).