Comprehensive analysis reveals high-risk drugs causing ketoacidosis, suggesting updates for medication safety.
The high-risk drugs for inducing ketoacidosis are mainly sodium-glucose cotransporter 2 (SGLT2) inhibitors (e.g., dapagliflozin and empagliflozin), followed by psychotropic drugs (e.g., quetiapine). Attention should also be paid to the potential risk of ketoacidosis induced by some drugs that do not mention this adverse reaction in their package inserts. The findings of this study can provide data support for clinical medication monitoring and the revision of drug package inserts.
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Du et al. (2026) studied this question.
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