What does this research mean for the field?

Green-synthesized chitosan-anchored Cu2O/ZnO nanocomposites provide highly efficient cisplatin release, selective toxicity against A375 melanoma cells with minimal fibroblast damage, and accelerated wound healing. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate the effectiveness of biogenic chitosan anchored Cu2O/ZnO nanocomposite for drug delivery and wound repair.

April 23, 2026RSC Pharmaceutics0 citationsOpen Access

Biogenic chitosan anchored Cu 2 O/ZnO nanocomposite: unlocking synergy for drug delivery, antineoplastic action, and wound repair

MNManojna R. Nayak RKRavindra R. Kamble LBLokesh Bheemayya

Key Points

The aim is to evaluate the effectiveness of biogenic chitosan anchored Cu2O/ZnO nanocomposite for drug delivery and wound repair.
Green synthesis of Cu2O/ZnO nanocomposite using S. campanulata fluid.
Analysis of cisplatin release at 72 hours.
Assessment of cytotoxicity on A375 melanoma and fibroblast cells.
Achieved 94.88% cisplatin release within 72 hours.
Demonstrated selective toxicity towards A375 melanoma cells with minimal fibroblast damage.
Showed significant enhancement in wound healing.

Abstract

Green-synthesized CS-Cu 2 O/ZnO NCs using S. campanulata fluid (WCF) offer 94.88% cisplatin release at 72h. They show selective A375 melanoma toxicity, low fibroblast damage, and fast wound healing, proving ideal for targeted cancer therapy and repair.

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Cite This Study

Nayak et al. (2026) studied this question.

synapsesocial.com/papers/69e9bc1285696592c86ed4b3 https://doi.org/10.1039/d5pm00392j

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April 23, 2026RSC Pharmaceutics0 citationsOpen Access

Biogenic chitosan anchored Cu 2 O/ZnO nanocomposite: unlocking synergy for drug delivery, antineoplastic action, and wound repair

MNManojna R. Nayak RKRavindra R. Kamble LBLokesh Bheemayya

Key Points

The aim is to evaluate the effectiveness of biogenic chitosan anchored Cu2O/ZnO nanocomposite for drug delivery and wound repair.
Green synthesis of Cu2O/ZnO nanocomposite using S. campanulata fluid.
Analysis of cisplatin release at 72 hours.
Assessment of cytotoxicity on A375 melanoma and fibroblast cells.
Achieved 94.88% cisplatin release within 72 hours.
Demonstrated selective toxicity towards A375 melanoma cells with minimal fibroblast damage.
Showed significant enhancement in wound healing.

Abstract

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Cite This Study

Nayak et al. (2026) studied this question.

synapsesocial.com/papers/69e9bc1285696592c86ed4b3 https://doi.org/10.1039/d5pm00392j

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View Full Paper