Definition and Evaluation of Transient Ischemic Attack
Authors
Discussion
Loading...
Member takes
Overview
Systematic review reveals high early stroke risk after transient ischemic attack, highlighting the need for rapid tissue-based neuroimaging and clinical risk stratification.
Key Points
- To establish an evidence-based, tissue-defined diagnostic framework and clinical evaluation protocol for transient ischemic attack.
- Conducted a systematic literature search in Medline covering studies published between 1990 and June 2007.
- Synthesized clinical data using evidence tables, meta-analyses, and pooled analyses of individual patient-level data.
- Formally established a tissue-based definition of transient ischemic attack as a brief episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia without acute tissue infarction.
- Identified substantial risk for early stroke recurrence, recommending neuroimaging within 24 hours using diffusion MRI alongside cervical and intracranial vessel evaluations.
- Supported emergency cardiac workups, routine blood testing, and hospital admission within 72 hours of symptom onset for patients with an ABCD(2) risk score of ≥3.
Cite This Study
Easton et al. (2009) studied this question.