Assessment of allopurinol use in patients with chronic kidney disease and asymptomatic hyperuricemia: a retrospective cohort study

Key Points

• To evaluate the impact of allopurinol on serum uric acid levels and kidney function in patients with chronic kidney disease and asymptomatic hyperuricemia.
• Conducted a retrospective cohort study involving patients with chronic kidney disease and asymptomatic hyperuricemia.
• Assessed serum uric acid levels and kidney function before and after allopurinol treatment.
• Allopurinol significantly reduced serum uric acid levels.
• Improvement in kidney function was noted.
• There was a delay in the progression to kidney failure among treated patients.