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This research models chemotherapy-induced mucositis in oral mucosa using a microfluidic platform, suggesting a new preclinical approach.
Oral-Mucosa-on-a-Chip The cover illustrates an oral mucosa-on-a-chip that reconstructs the complex microenvironment of human oral mucosa. A stratified epithelium, lamina propria, and vascular layers are integrated within a microfluidic platform to reproduce key physiological functions. This platform enables investigation of chemotherapy-induced mucositis, supports drug response evaluation, and provides a promising alternative to conventional animal models in preclinical studies. More information can be found in the Research Article by Hyo-Il Jung, Bongseop Kwak, Bo Hae Kim, and co-workers (10.1002/adfm.202521887).
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Kim et al. (2026) studied this question.
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