Light-Driven EDA–APEX Approach: A One-Pot Access to Phenanthrenes and Naphthalenes

Vishal Jyoti Roy; Sisira Santhosh; Kajal Tiwari; G Kiran Kumar; Janardan Chakraborty; Krishnapriya Anattil Unnikrishnan; Rositha Kuniyil; Sudipta Raha Roy

doi:10.1021/acs.orglett.6c01071

April 21, 2026Organic Letters

Light-Driven EDA–APEX Approach: A One-Pot Access to Phenanthrenes and Naphthalenes

View at Publisher

Ask AI

Bookmark

Share

Key Points

The research aims to develop a light-driven, transition-metal-free method for synthesizing phenanthrenes and naphthalenes.
Utilized anion-π initiation
Employed O2-mediated pathways
Performed in a one-pot synthesis approach
Achieved up to 95% yield of phenanthrenes
Demonstrated high regioselectivity
Facilitated access to diverse naphthalene derivatives

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

This method describes a light-driven synthesis of phenanthrenes and naphthalenes with high yield and regioselectivity, suggesting a new pathway for organic synthesis.

Abstract

We report a light-driven, transition-metal-free annulative π-extension (APEX) that affords phenanthrenes in up to 95% yield with high regioselectivity. This anion-π-initiated, O₂-mediated one-pot method avoids pre-functionalization, tolerates diverse substituents, and also enables access to naphthalene derivatives.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Roy et al. (2026) studied this question.

synapsesocial.com/papers/69eb084f553a5433e34b35be https://doi.org/10.1021/acs.orglett.6c01071

View at Publisher

Ask AI

Bookmark

Share

Light-Driven EDA–APEX Approach: A One-Pot Access to Phenanthrenes and Naphthalenes

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Light-Driven EDA–APEX Approach: A One-Pot Access to Phenanthrenes and Naphthalenes

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading