Asymmetric Oxidative Rearrangement of Tetrahydro-β-Carbolines Catalyzed by Anionic Stereogenic-at-Cobalt(III) Complexes

Key Points

• The research aims to explore a new cobalt(III)-catalyzed method for synthesizing chiral spirooxindoles from tetrahydro-β-carbolines.
• Developed an asymmetric oxidative rearrangement process.
• Utilized anionic stereogenic-at-cobalt(III) complexes as catalysts.
• Synthesis of a range of products was demonstrated.
• Successfully synthesized various chiral spirooxindoles.
• Showed distinct effectiveness of cobalt-based catalytic mode.
• Demonstrated a new pathway for oxidative rearrangement.