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April 24, 2026JAC-Antimicrobial Resistance2 citationsOpen Access

2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK

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ANAnn L. NobleSPSanjay PatelEBEllie Birnie

Key Points

  • To provide updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK.
  • Reviewed existing literature regarding OPAT
  • Conducted expert consensus consultations
  • Developed quality indicators based on findings
  • Established updated GPRs for OPAT in both adults and children
  • Enhanced guidance for safe and effective OPAT delivery
  • Included quality indicators applicable across various OPAT service models

Abstract

Abstract Good practice recommendations (GPRs) for outpatient parenteral antimicrobial therapy (OPAT) in the UK were first published in 2012 and 2015 for adult and paediatric OPAT, respectively, and then updated in 2019 as a combined set of recommendations for OPAT in all age groups. Since then, there has been ongoing expansion in national and global experience of OPAT. Here, we provide updated 2026 GPRs developed through a further review of the literature, expert consensus, and extensive consultation. As previously, these updated GPRs for OPAT in adults and children will support delivery of safe and effective OPAT by providing a set of quality indicators for OPAT in the UK regardless of the setting or service model.

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Cite This Study

Noble et al. (2026) studied this question.

synapsesocial.com/papers/69eb099a553a5433e34b4056https://doi.org/10.1093/jacamr/dlag044
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