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April 24, 2026ACS OmegaOpen Access

Noncalcined Bioactive Glass/Fish Scale Gelatin Hybrids Prepared by Sol–Gel Processing for Enhanced In Vitro Bioactivity

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Authors

RBR. BuntemMaterials Design (France)MSMonthita SasanaSilpakorn UniversityPNPhimmada NithipongwarodomSilpakorn University

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Implication

Demonstrates enhanced bioactivity in fish scale gelatin and bioactive glass scaffolds, suggesting promising applications for bone tissue engineering.

Key Points

  • The aim is to evaluate the bioactivity of a new composite scaffold made from fish scale gelatin and bioactive glass.
  • Extracted fish scale gelatin using acid-alkaline treatment and heat extraction.
  • Synthetized bioactive glass using a sol-gel method and combined it with gelatin to form a composite scaffold.
  • Characterized the materials using various analytical techniques including FTIR and SEM-EDX.
  • Scaffold demonstrated compressive strength of 7.63 MPa, surpassing the strength of pure bioactive glass.
  • Hydroxyapatite formation was observed on the scaffold surface, indicating good bioactivity.
  • Calcium ion concentration changes suggested favorable conditions for bone growth.

Cite This Study

Buntem et al. (2026) studied this question.

synapsesocial.com/papers/69eb0a2e553a5433e34b4648https://doi.org/10.1021/acsomega.5c13426
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