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Systematic review highlights advanced ageing in schizophrenia, suggesting new research directions.
Schizophrenia is associated with a multisystem ageing phenotype underpinned by convergent biological mechanisms, most consistently involving telomere attrition and oxidative and/or inflammatory stress. The overall pattern supports a model of advanced rather than uniformly accelerated ageing, reflecting early biological deviation with parallel rather than steeper decline.
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Fernández-Egea et al. (2026) studied this question.
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