Nitrogen Editing of Aromatic Rings: From Skeletal Editing to Fragment Editing

Key Points

• This research aims to investigate the direct conversion of aromatic rings into heteroaromatic frameworks to enhance molecular properties.
• Examined different molecular editing techniques.
• Focused on skeletal and fragment editing methods.
• Evaluated the impact of changes on properties relevant to pharmaceuticals.
• Demonstrated successful conversion of aromatic rings using nitrogen editing.
• Identified enhancements in molecular properties for applications in functional materials.
• Highlighted the versatility of molecular editing strategies in pharmaceutical development.