Nitrogen Editing of Aromatic Rings: From Skeletal Editing to Fragment Editing

Hikaru Nakahara; Junichiro Yamaguchi

doi:10.1039/d6cc01696k

January 1, 2026Chemical CommunicationsOpen Access

Nitrogen Editing of Aromatic Rings: From Skeletal Editing to Fragment Editing

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Key Points

This research aims to investigate the direct conversion of aromatic rings into heteroaromatic frameworks to enhance molecular properties.
Examined different molecular editing techniques.
Focused on skeletal and fragment editing methods.
Evaluated the impact of changes on properties relevant to pharmaceuticals.
Demonstrated successful conversion of aromatic rings using nitrogen editing.
Identified enhancements in molecular properties for applications in functional materials.
Highlighted the versatility of molecular editing strategies in pharmaceutical development.

Implication

Research explores nitrogen editing effects on aromatic rings, indicating potential for improving pharmaceutical applications.

Abstract

Direct conversion of aromatic rings into heteroaromatic frameworks represents an attractive strategy for tuning molecular properties in pharmaceuticals and functional materials. In recent years, the concept of molecular editing has...

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Cite This Study

Nakahara et al. (2026) studied this question.

synapsesocial.com/papers/69eb0bc7553a5433e34b5622 https://doi.org/10.1039/d6cc01696k

View Full Paper

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Nitrogen Editing of Aromatic Rings: From Skeletal Editing to Fragment Editing

Key Points

Implication

Abstract

Discussion

Cite This Study

Nitrogen Editing of Aromatic Rings: From Skeletal Editing to Fragment Editing

Key Points

Implication

Abstract

Discussion

Cite This Study

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