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April 30, 1993Statistics in Medicine629 citations

Kaplan—meier, marginal or conditional probability curves in summarizing competing risks failure time data?

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MPMargaret S. PepeDartmouth CollegeMMMotomi MoriSt. Jude Children's Research Hospital

Key Points

  • To evaluate the suitability of alternative descriptive estimators and two-sample test statistics for summarizing failure time data in the presence of competing risks.
  • Assessed the descriptive validity of the standard Kaplan-Meier estimator in competing risk settings.
  • Examined marginal probability and conditional probability estimators as alternative summarization techniques.
  • Presented two-sample test statistics designed for comparative analysis of competing risk failure time data.
  • Demonstrated that the standard Kaplan-Meier estimator is frequently unsuitable for summarizing survival data when competing risks are present.
  • Showed that marginal and conditional probability estimators provide viable descriptive alternatives for summarizing failure time curves and calculating two-sample comparisons.

Abstract

In the context of competing risks the Kaplan-Meier estimator is often unsuitable for summarizing failure time data. We discuss some alternative descriptive methods including marginal probability and conditional probability estimators. Two-sample test statistics are also presented.

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Cite This Study

Pepe et al. (1993) studied this question.

synapsesocial.com/papers/69ec00e2c50e673b4ec2fc5ehttps://doi.org/10.1002/sim.4780120803
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Review and Critique of Some Models Used in Competing Risk Analysis1975 · 248 citations
  2. 2Inference for Events with Dependent Risks in Multiple Endpoint Studies1991 · 230 citations
  3. 3Regression Models and Life-Tables1972 · 39,703 citations
  4. 4A nonidentifiability aspect of the problem of competing risks.1975 · 869 citations
  5. 5Smoothing Counting Process Intensities by Means of Kernel Functions1983 · 517 citations