Key result
Virulent and attenuated DHAV-3 elicit divergent duck liver transcriptomes, highlighting IFN-I signaling in antiviral immunity.
IFN-I signaling serves as a central axis in the antiviral immune response to DHAV-3 in ducks.
Provides a corrected transcriptomic baseline for viral hepatitis in an avian model; leaves open any translational.
A Correction on: Fu Q, Jiao W, Wan C, Wang W, Su J, Liu X, Cheng L, Chen H, Liu J, Huang Y and Fu G (2026) Comparative analysis of ducks liver gene expressions infected with virulent or attenuated DHAV-3 reveals divergent host responses to viruses of different virulence. Front. Microbiol. 17:1740464. doi: 10.3389/fmicb.2026.1740464A correction has been made to the section [Abstract: Discussion]: "These findings delineate divergent host transcriptomic responses to virulent vs. attenuated DHAV-3 and highlight IFN-I signaling as a central axis in antiviral immunity."The original version of this article has been updated.
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Frontiers Production Office (2026) studied DHAV-3 infection. Virulent DHAV-3 vs. Attenuated DHAV-3 was evaluated on Host transcriptomic responses. Virulent and attenuated DHAV-3 elicit divergent host transcriptomic responses in duck liver, highlighting IFN-I signaling as a central axis in antiviral immunity.
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