Why the study?
Does open heart mitral valve replacement using the Edwards-Sapien 3 prevent left ventricular outflow tract obstruction in patients with severe mitral annular calcification?
Does open heart mitral valve replacement using the Edwards-Sapien 3 prevent left ventricular outflow tract obstruction in patients with severe mitral annular calcification?
Open heart implantation of a transcatheter valve (Edwards-Sapien 3) with anterior leaflet resection is a safe surgical approach for severe mitral annular calcification that avoids decalcification and prevents LVOT obstruction.
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Should not yet change practice in severe mitral annular calcification; leaves open confirmation of open-heart Sapien 3 implantation in prospective trials.
Morita et al. (2021) studied this question.
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