Why the study?
Does clopidogrel plus aspirin improve safety and tolerability compared to ticlopidine plus aspirin in patients after coronary stenting?
Population
Patients after successful coronary stenting
Comparison
Clopidogrel in combination with aspirin vs Ticlopidine in combination with aspirin
Design
RCT, Double-blind
Authors
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Supports clopidogrel plus aspirin as preferred post-stent dual therapy; reinforces safer alternative to ticlopidine with maintained efficacy.
Does clopidogrel plus aspirin improve safety and tolerability compared to ticlopidine plus aspirin in patients after coronary stenting?
Clopidogrel plus aspirin provides superior safety and tolerability compared to ticlopidine plus aspirin after coronary stenting, while maintaining comparable efficacy for preventing cardiac events.
Bertrand et al. (2000) studied this question.
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