Key result
Adjunctive tirofiban during endovascular thrombectomy significantly reduced 90-day mortality (RR 0.89) and increased functional independence in patients with acute ischemic stroke.
Why the study?
While intravascular lithotripsy (IVL) and coronary atherectomy are established for calcified lesions, comparative outcomes in post-TAVR patients remain unclear.
Meta-Analysis (n=5,536)
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Shah et al. (2026) conducted a meta-analysis in Acute ischemic stroke (n=5,536). Tirofiban vs. Control was evaluated on Mortality within 90 days of stroke (RR 0.89, 95% CI 0.79-1.00, p=0.05). Adjunctive tirofiban during endovascular thrombectomy significantly reduced 90-day mortality (RR 0.89) and increased functional independence in patients with acute ischemic stroke.
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