Why the study?
IVUS adoption in PCI practice has been lower than expected despite guideline endorsement and upgrade to a class 2a recommendation for left main disease.
Does physiology-guided PCI using FFR or iFR reduce mortality and myocardial infarction in frail patients aged ≥80 years compared to angiography-guided PCI alone?
Does physiology-guided PCI using FFR or iFR reduce mortality and myocardial infarction in frail patients aged ≥80 years compared to angiography-guided PCI alone?
In frail patients aged ≥80 years undergoing PCI, physiology-guided intervention with FFR or iFR is associated with significantly lower 1-year mortality and myocardial infarction compared to angiography alone.
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Baig et al. (2026) studied this question.
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