This research aims to explore the relationship between CTLA-4 haploinsufficiency and oral lichenoid lesions driven by IFN-γ.
Assessing the immunopathological characteristics of oral lichenoid lesions in individuals with CTLA-4 haploinsufficiency.
Analyzing mucosal immune responses to understand the impact of IFN-γ in this context.
Identification of specific immunological pathways influenced by CTLA-4 haploinsufficiency, implicating significant roles of IFN-γ.
Potential therapeutic targets emerged for treating oral lichenoid lesions in affected individuals.
Abstract
The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.