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Investigates fluid speed effects on glycocalyx and blood volume in a porcine septic shock model, suggesting implications for treatment.
There was no difference in glycocalyx degradation or vascular shear stress between an IVF bolus given over 5 min compared with 20 min. Central blood volumes trended greater in the slow IVF group compared with the fast IVF group.
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Levenbrown et al. (2026) studied this question.
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