Analysis reveals increasing drug-related burden and health inequalities across countries.
Despite declining global age standardised rates since 1990, SUDs remain a major source of health loss, with pronounced age-sex differences, substantial cross-country heterogeneity, and widening divergence by development level. Recent increases in drug-related burden in some high-SDI settings highlight the need for strengthened surveillance and context-specific prevention, treatment, and harm-reduction responses.
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Yu et al. (2026) studied this question.
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