Stroke Etiologies With Intravenous Thrombolysis before Thrombectomy and Functional Outcomes in Anterior Circulation Large Vessel Occlusion

Key Points

• To assess the impact of stroke etiologies on the efficacy and safety of intravenous thrombolysis (IVT) prior to thrombectomy (EVT) in patients with large vessel occlusion (LVO).
• Evaluated patients with LVO presenting to EVT-capable centers
• Analyzed outcomes of IVT before EVT
• Investigated specific stroke etiologies and their effects on outcomes.
• No significant modification in efficacy or safety of IVT based on stroke etiologies.
• Isolated benefit noted in other/undetermined subgroup, pending confirmation.