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April 23, 2026International Endodontic JournalOpen Access

Factors Associated With Endodontic Flare‐Ups: A Systematic Review and Meta‐Analysis

Jun Ohshima Masayoshi Morita 川西雄三 Shotaro Abe Nobutake Tanaka Tsuyoshi Shimaoka Hazuki Maezono Yoshifumi Kinomoto Mikako Hayashi

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Key Points

The aim is to identify and analyze factors associated with endodontic flare-ups.
Conducted a systematic review following the PROSPERO registration.
Performed a meta-analysis to quantify the relationships of identified factors.
Included relevant studies that reported on risk factors leading to flare-ups.
Several risk factors for endodontic flare-ups were identified, enhancing understanding of complications.
Quantitative analysis provided statistics on how often these risk factors lead to flare-ups.

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Implication

Systematic review identifies risk factors for endodontic flare-ups, suggesting areas for improved clinical practice.

Abstract

PROSPERO Systematic review registration number: CRD420251025451.

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Cite This Study

Ohshima et al. (2026) studied this question.

synapsesocial.com/papers/69edac9b4a46254e215b454d https://doi.org/10.1111/iej.70164

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