Preclinical evaluation of new terpenyl-cinnamoyl-hydrazone analogues shows potential antinociceptive effects in nociception models, suggesting therapeutic value.
In this study, novel terpenyl-cinnamoyl-hydrazone analogs were synthesized and evaluated for antinociceptive potential in preclinical nociception models. The compounds were tested in chemical (formalin-induced licking) and thermal (hot plate) assays...
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Paiva et al. (2026) studied this question.
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