What question did this study set out to answer?

This research aims to evaluate if surgical outcomes for moderate to large angle exotropia are better predicted by surgical dosage or pre-operative exotropia angle.

April 26, 2026Japanese Journal of OphthalmologyOpen Access

Challenge to the concept of surgical dose-response for moderate to large angle exotropia

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Authors

SSSoh Youn SuhUniversity of California, Los Angeles QMQingyu Meng ATAmi TamhaneyUniversity of California, Los Angeles

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Implication

Retrospective interventional case study analyzes surgical dosage versus pre-operative angle in exotropia outcomes, suggesting a biological response predominates.

Key Points

This research aims to evaluate if surgical outcomes for moderate to large angle exotropia are better predicted by surgical dosage or pre-operative exotropia angle.
Retrospective analysis of cases with 30–55Δ exotropia undergoing specific muscle surgeries between 2014 and 2024.
Patients had bilateral lateral rectus recession and unilateral medial rectus plication, with surgical effects analyzed by linear regression.
Success defined as less than 10Δ exotropia or 5Δ esotropia post-operatively.
34 patients analyzed with mean preoperative exotropia of 42 ± 6Δ at distance.
Average surgical effect was 42 ± 10Δ with a mean dose response of 2 ± 1Δ/mm.
Success rate for all angles was 76% at 2 months follow-up.

Cite This Study

Suh et al. (2026) studied this question.

synapsesocial.com/papers/69edad094a46254e215b4bba https://doi.org/10.1007/s10384-026-01344-1

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Implication

Retrospective interventional case study analyzes surgical dosage versus pre-operative angle in exotropia outcomes, suggesting a biological response predominates.

Challenge to the concept of surgical dose-response for moderate to large angle exotropia

Discussion

Member takes

Implication

Key Points

Cite This Study

Challenge to the concept of surgical dose-response for moderate to large angle exotropia

Discussion

Member takes

Implication

Key Points

Cite This Study

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