Key result
A 1.8 mm coronary angioscope enables feasible in vivo intravascular visualization during cardiac surgery.
Why the study?
The feasibility and clinical usefulness of direct in vivo coronary angioscopy for visualizing intravascular anatomy and disease were not established.
Is in vivo coronary angioscopy feasible for direct visualization of intravascular anatomy and disease?
Is in vivo coronary angioscopy feasible for direct visualization of intravascular anatomy and disease?
This early feasibility study demonstrated that direct in vivo visualization of coronary anatomy using a 1.8 mm angioscope is possible.
Offers new intraoperative visualization avenue but should not yet change practice; leaves open safety, efficacy, and nonsurgical translation.
The feasibility of in vivo coronary angioscopy was tested utilizing a 1.8 mm angioscope in vessels where blood had been replaced by optically clear liquids, including a new perfluorocarbon emulsion. After trials in postmortem canine and human coronary arteries, in vivo intraluminal visualization was accomplished in the dog with a catheterization technique and in patients during open heart surgery. The results demonstrate the feasibility and potential clinical usefulness of direct visualization of intravascular anatomy and disease, analogous to endoscopy of other organ systems.
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Spears et al. (1983) studied Patients undergoing open heart surgery. In vivo coronary angioscopy utilizing a 1.8 mm angioscope was evaluated on Feasibility of in vivo intraluminal visualization. In vivo coronary angioscopy using a 1.8 mm angioscope was demonstrated to be feasible for direct visualization of intravascular anatomy in dogs and in patients during open heart surgery.
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