Why the study?
Premature CAD features a high burden of non-calcified plaque and high-risk plaque contributing to progression and recurrences, and qualitative CCTA assessment may improve risk stratification beyond cardiovascular risk factors.
Qualitative CCTA assessment of plaque characteristics may improve risk stratification in patients with premature CAD beyond traditional cardiovascular risk factors.
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CCTA plaque characterization may refine risk stratification in premature CAD; leaves open prospective outcome validation before clinical adoption.
Coronary atherosclerosis in individuals with premature CAD is characterized by a high and predominant burden of non-calcified plaque and unusual high prevalence of HRP, contributing to disease progression with multiple recurrences. A comprehensive qualitative CCTA assessment of plaque characteristics may further risk stratify our patients, beyond cardiovascular risk factors.
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Rahoual et al. (2023) studied this question.
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