Why the study?
Does 12 months of dual antiplatelet therapy prevent stent thrombosis, myocardial infarction, and death in patients with coronary artery stents?
Does 12 months of dual antiplatelet therapy prevent stent thrombosis, myocardial infarction, and death in patients with coronary artery stents?
This advisory emphasizes the critical importance of completing 12 months of dual antiplatelet therapy after drug-eluting stent placement to prevent severe cardiac events.
Adhere to 12-month DAPT post-DES and delay elective surgery 1 year; reinforces consensus on minimizing stent thrombosis.
Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after placement of a drug-eluting stent and educating the patient and healthcare providers about hazards of premature discontinuation. It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents.
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Grines et al. (2007) studied this question.
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