Why the study?
Does distal protection reduce microcirculation damage and left ventricular dysfunction in patients with AMI who had angioscopically defined ruptured plaque?
Does distal protection reduce microcirculation damage and left ventricular dysfunction in patients with AMI who had angioscopically defined ruptured plaque?
Distal protection mitigates microcirculation damage and left ventricular dysfunction caused by distal embolization of plaque debris in AMI patients with ruptured plaque.
Supports distal protection in AMI with angioscopically ruptured plaque; extends evidence for targeted embolization prevention.
Distal protection reduced microcirculation damage and left ventricular dysfunction in patients with AMI who had angioscopically defined ruptured plaque. Distal embolization of plaque debris was detected more frequently in patients with ruptured plaque. These results suggest that microcirculation damage and left ventricular dysfunction are increased mainly by distal embolization of plaque debris rather than of thrombus.
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Mizote et al. (2005) studied this question.
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