Why the study?
Are carotid plaque, coronary artery calcium, or abnormal ankle pressures valid indicators of subclinical atherosclerosis in asymptomatic people?
Are carotid plaque, coronary artery calcium, or abnormal ankle pressures valid indicators of subclinical atherosclerosis in asymptomatic people?
Carotid plaque, coronary artery calcium, and abnormal ankle pressures are valid surrogate markers of subclinical atherosclerosis for use in research studies.
Answers are grounded in this paper and cite their sources.
Supports these markers as research surrogates; leaves open routine clinical screening in asymptomatic adults.
The presence of carotid plaque, coronary artery calcium, or abnormal ankle pressures seems to be a valid indicator of the presence of subclinical atherosclerosis and may be considered for use in biomarker, Mendelian randomization and similar studies.
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Garg et al. (2023) studied this question.
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