Key result
Asymptomatic carotid atherosclerosis with stenotic plaques (≥50% stenosis) was associated with an increased risk of cardiovascular events compared to no plaques (HR 3.05; 95% CI 1.62-5.74).
Why the study?
Does the severity of asymptomatic carotid atherosclerosis predict the development of cardiovascular diseases in older adults?
Cohort (n=1,376)
Does the severity of asymptomatic carotid atherosclerosis predict the development of cardiovascular diseases in older adults?
Hazard Ratio: 3.05 (95% CI 1.62–5.74)
The severity of asymptomatic carotid atherosclerosis, specifically the presence of plaques, independently predicts the 5-year risk of cardiovascular events in older Chinese adults.
Authors
No takes yet. Share an insight, caveat, or question.
No significant CVD association with minimal CAS; leaves open mild carotid atherosclerosis for risk stratification in observational cohorts.
Zhang et al. (2017) conducted a cohort in Asymptomatic carotid atherosclerosis (n=1,376). Asymptomatic carotid atherosclerosis (stenotic plaques) vs. No CAS (CCA-IMT <1 mm and no plaques) was evaluated on New CVD events, including stroke and coronary heart events (HR 3.05, 95% CI 1.62-5.74). Asymptomatic carotid atherosclerosis with stenotic plaques (≥50% stenosis) was associated with an increased risk of cardiovascular events compared to no plaques (HR 3.05; 95% CI 1.62-5.74).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: