January 27, 2017European Journal of Preventive CardiologyOpen Access

Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases

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Population

24,822 Chinese adults from 10 geographical regions in the China Kadoorie Biobank and 2,579 European adults…

Design

Cross-sectional

Authors

RCRobert ClarkeUniversity College Hospital HDHuaidong DuGeneral / Preventive / Lipids OKOm KurmiNational Academy of Medical Sciences

Discussion

Member takes

Implication

Indicates greater subclinical atherosclerosis burden in Chinese adults; leaves open whether ethnicity-specific prevention strategies are warranted.

Structured PICO

Population

24,822 Chinese adults (mean age 59 years, 38% male) from 10 geographical regions in the China Kadoorie Biobank and 2,579 European adults (mean age 62 years) from the UK Biobank.

Outcome

Mean intima-media thickness (cIMT) of the common carotid arteries and presence of carotid artery plaquesurrogate

Chinese adults have a substantial burden of carotid atherosclerosis that progresses more steeply with age compared to European populations, highlighting a high future risk of cardiovascular disease in China.

Limitations

Data on plaque were limited to presence of plaques, plaque thickness, and plaque number, lacking information on plaque vulnerability such as necrotic core or echolucency.

Cite This Study

Clarke et al. (2017) studied this question.

synapsesocial.com/papers/6a84b3142cc9708cfc15afdf https://doi.org/10.1177/2047487317689973

Topics

Women and heart disease

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Implication

Indicates greater subclinical atherosclerosis burden in Chinese adults; leaves open whether ethnicity-specific prevention strategies are warranted.